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It's about restoring or amplifying what should already be happening which is why the side effect profiles of most therapeutic peptides are generally favorable, and why this category of treatment has attracted significant clinical research interest over the past decade

2 ) in several randomized, controlled trials that compared it to placebo and other antidepressants, such as fluoxetine, paroxetine citalopram, trazodone, amitriptyline, doxepin, clomipramine, imipramine, and venlafaxine (Richou et al

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Importantly, ferroptosis is related to ROS, redox glutathione (GSH), GPX4, iron ions (Fe 3+ , Fe 2+ ) in cells, and lipid peroxidation, which involves some pathways (Figure 1 and Table 1)